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Breast Cancer Guidelines Carve Out Category for Low ER Expression - OncLive

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W. Fraser Symmans, MD, a professor and director of research operations in the Department of Pathology at The University of Texas MD Anderson Cancer Center

W. Fraser Symmans, MD

The American Society of Clinical Oncology (ASCO) and College of American Pathologists (CAP) have further refined their recommendations for estrogen receptor (ER) and progesterone receptor (PgR) testing protocols in patients with breast cancer. The latest update offers guidance for interpreting a new reporting category— ER-low–positive cancers, which are defined as breast cancer samples with 1% to 10% of tumor nuclei staining positive for ER (Table 1).1
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