Supplemental ultrasound screening paired with mammography can potentially improve cancer detection across all breast types, according to new research published in JAMA Network Open.
The go-to modality for this disease has been shown to reduce deaths, but mammography’s sensitivity plummets for those with dense tissue. Ultrasound, however, is showing promise improving those rates, Japanese researchers reported Aug. 18. The findings were derived from a secondary analysis of a randomized control trial incorporating more than 19,000 women.
“Adjunctive ultrasonography had good screening balance with mammography regardless of breast density, detecting early stage and invasive malignant lesions for asymptomatic women with average risk of breast cancer,” Narumi Harada-Shoji, MD, PhD, with the Department of Breast and Endocrine Surgical Oncology at Tohoku University in Sendai, Japan, and co-authors concluded. “Thus, adjunctive ultrasonography should be considered as an optimal solution in young women with average risk.”
For the study, scientists utilized data from the Japan Strategic Anti-Cancer Randomized Trial, incorporating asymptomatic women in their 40s screened between 2007 to 2020. Participants were randomly assigned to undergo either mammography with ultrasound (9,705 women) or mammo alone (9,508 more). Nearly 11,400 (or 59%) had heterogeneously or extremely dense breasts, and providers detected 130 cancers among the overall group.
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August 24, 2021 at 01:14PM
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Supplemental ultrasound screening with mammography improves cancer detection across all breast types - Radiology Business
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